WebbMy research has been primarily focused on identifying novel therapeutic targets and diagnostic markers in various types of solid and hematological malignancies, utilizing cutting-edge technologies... WebbHe also runs a research laboratory at the Gladstone Institutes, where he investigates how disruptions of mitochondria—the “power centers” of cells that convert nutrients into energy—contribute to the development and progression of Parkinson’s disease and Alzheimer’s disease.
HIPK2—A therapeutical target to be (re)activated for tumor …
WebbHomeodomain-interacting protein kinase 2 (HIPK2) is a conserved serine/threonine kinase, which regulate transcription, cell differentiation, proliferation and … Webb14 okt. 2009 · However, we recently reported that hypoxic-induced HIPK2 inhibition can be completely restored by zinc supplementation that reactivates p53 apoptotic response to … drivermax windows xp
Critical role of Bid and Bax in indirubin-3′-monoxime-induced …
Webb15 jan. 2024 · WST-8 assay. Cells at a density of 5.0 × 10 4 cells/mL were plated in a 96-well plate and divided into five groups: miR-21-5p group (miR-2-5p over-expression), NC group (infected with negative control lentiviral vector), control group (no infection), sh-Tiam1 group (infected with lentiviral vector expressing short hairpin (sh)-Tiam1), and sh … Webb9 dec. 2015 · The (re)emergence of new influenza viruses or SARS-CoV-2 variants, confirms that we are in front of recurrent and unpredictable risk of epidemics and pandemic. Additionally, limits of the current prophylactic and therapeutic arsenal (deadline/unavailability of vaccination and antiviral resistance) require the development … Webb31 maj 2010 · HIPK2 is activated by numerous genotoxic agents and can be deregulated in tumors by several conditions including hypoxia. Recent findings suggest that HIPK2 … e pill watch