Dclk1 macrophage
WebDCLK1 is a proposed cancer driver gene, and its upregulation is associated with poor overall survival in several solid cancer types. However, how DCLK1 associates with MTs and how its kinase... WebJun 17, 2024 · Significant co-localization of DCLK1 with both CD68 and CD11c representing macrophages and dendritic cells, respectively, was recorded in the sub-mucosal …
Dclk1 macrophage
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WebApr 29, 2024 · Capture of the inflammatory cytokine interleukin (IL)-1β (and others) at an mRNA level may be limited, as the bioactive form of IL-1β, which has a major role in triggering DATPs 25, is generated by... WebNov 26, 2024 · Double cortin-like kinase 1 (Dclk1), a marker of intestinal tuft cells, can regulate tissue regenerative responses, but its role in epithelial repair during bacterial-dependent chronic colitis is...
WebJul 2, 2024 · Doublecortin-like kinase 1 (DCLK1) is a marker of tumor stem cells, which identifies the progenitors and cell of origin in inflammation-associated mouse pancreatic cancer ( 9–11 ). DCLK1 is overexpressed … http://bio-bigdata.hrbmu.edu.cn/CellMarker/index.html
WebNov 16, 2024 · Notably, in pancreatic adenocarcinoma, overexpression of DCLK1 in tumor cells has been shown to educate M2 macrophages resulting in CD8+ T-cell suppression, whereas silencing DCLK1 has the reverse effect . Despite these interesting findings, the influence of DCLK1 kinase inhibitors on anti-tumor immunity has not been previously … WebDoublecortin-like kinase 1 (DCLK1), a microtubule-associated protein kinase, is involved in neurogenesis and human cancers. However, the role of DCLK1 in atherosclerosis …
WebMar 22, 2024 · Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1's elimination during colon cancer development and progression Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1's elimination during colon cancer development and …
WebAug 3, 2024 · Dandawate, P. et al. The histone demethylase KDM3A, increased in human pancreatic tumors, regulates expression of DCLK1 and promotes tumorigenesis in mice. Gastroenterology157, 1646–1659 e1611 ... david linthicum chargesWebDoublecortin-like kinase 1 activates NF-κB to induce inflammatory responses by binding directly to IKKβ Doublecortin-like kinase 1 activates NF-κB to induce inflammatory responses by binding directly to IKKβ Cell Death Differ. 2024 Mar 13. doi: 10.1038/s41418-023-01147-8. Online ahead of print. Authors david linthicum cockeysville mdWebApr 1, 2024 · Macrophages Dclk1 Tuft Cells Colitis-Associated Cancer Abbreviations used in this paper AOM azoxymethane CD Crohn’s disease CLD clodronate CRC colorectal cancer DSS dextran sodium sulfate IBD inflammatory bowel disease IL interleukin MPO myeloperoxidase oxazolone 4-ethoxylmethylene-2-phenyloxazol-5-one TNBS 2,4,6 … david linsley homes raleighWebMay 5, 2024 · Request PDF DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization Tumor-associated M2-macrophages are one of the most abundant ... david linthicum cloud computing podcastWebDCLK1 expression was negatively associated with the infiltration of both CD8+ cytotoxic T-cells and active NK cells and positively associated with the immunosuppressive M2 macrophage populations ... david linthicum mdWebHuman. Welcome to CellMarker 2.0. Microglial cell (523) Astrocyte (499) Neuron (205) other 261 cells. SLC16A7+ cell (1190) Ciliated cell (319) david lin orthopedics kingwoodWebTUFT cells have been described as strong modulators of inflammatory cells in several tissues including pancreas. TUFT cells, also known as DCLK1+ cells, are dependent of the transcriptional factor POU2F3. Several works report DCLK1+ cells in early stages of PDAC development suggesting an important role of TUFT cells in PDAC development. … gas scooter store near me