WebMar 21, 2024 · CCND1 (Cyclin D1) is a Protein Coding gene. Diseases associated with CCND1 include Von Hippel-Lindau Syndrome and Myeloma, Multiple . Among its related pathways are Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects and Regulation of activated PAK-2p34 by proteasome mediated degradation . WebJul 10, 2015 · 2015年7月6日，清华大学生命科学学院王一国研究组在Nature在线发表论文《CREB的转录激活因子CRTC2通过SREBP1调控肝脏脂代谢》（The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1），报道了环磷酸腺苷反应元件结合蛋白（CREB）的转录激活因子（CRTC2）调控脂代谢的信号通路，揭示了代 …
Bcl-2、细胞凋亡以及肿瘤靶向治疗 - 知乎 - 知乎专栏
BCL-2 is localized to the outer membrane of mitochondria, where it plays an important role in promoting cellular survival and inhibiting the actions of pro-apoptotic proteins. The pro-apoptotic proteins in the BCL-2 family, including Bax and Bak, normally act on the mitochondrial membrane to … See more Bcl-2 (B-cell lymphoma 2), encoded in humans by the BCL2 gene, is the founding member of the Bcl-2 family of regulator proteins that regulate cell death (apoptosis), by either inhibiting (anti-apoptotic) or inducing (pro … See more Damage to the Bcl-2 gene has been identified as a cause of a number of cancers, including melanoma, breast, prostate, chronic lymphocytic leukemia, and See more Targeted and selective Bcl-2 inhibitors that have been in development or are currently in the clinic include: Oblimersen An antisense oligonucleotide drug, oblimersen (G3139), was developed by Genta Incorporated to … See more • Apoptosome • Bcl-2 homologous antagonist killer (BAK) • Bcl-2-associated X protein (BAX) See more The two isoforms of Bcl-2, Isoform 1, and Isoform 2, exhibit a similar fold. However, results in the ability of these isoforms to bind to the BAD and BAK proteins, as well as in the structural topology and electrostatic potential of the binding groove, suggest … See more Antibodies to Bcl-2 can be used with immunohistochemistry to identify cells containing the antigen. In healthy tissue, these antibodies react with B-cells in the mantle zone, as well as some T-cells. However, positive cells increase considerably in See more Bcl-2 has been shown to interact with: • BAK1, • BCAP31, • BCL2-like 1, • BCL2L11, • BECN1, See more extra long shower curtain walmart
BCL2L1 癌基因 - 癌症123
WebMar 21, 2024 · BCL2 (BCL2 Apoptosis Regulator) is a Protein Coding gene. Diseases associated with BCL2 include Follicular Lymphoma and High-Grade B-Cell Lymphoma Double-Hit/Triple-Hit.Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway.Gene Ontology (GO) annotations related to this gene … http://fund.keyanzhiku.com/Index/info/id/NDI2NTg0ODg0YmllLXNoaS1sZS1xdS1iaWUtcmVuLWppYS1wYS1zaHUtanUtYmE%3D.html WebMar 21, 2024 · BCL2 (BCL2 Apoptosis Regulator) is a Protein Coding gene. Diseases associated with BCL2 include Follicular Lymphoma and High-Grade B-Cell Lymphoma … extra long shower curtain with tassels